Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer
Status:
Completed
Trial end date:
2016-07-11
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel, carboplatin, and cisplatin, work
in different ways to stop the growth of tumor cells, either by killing the cells or by
stopping them from dividing. Giving more than one drug (combination chemotherapy) and giving
them in different ways may kill more tumor cells. It is not yet known which combination
chemotherapy regimen is more effective in treating patients with ovarian epithelial cancer,
primary peritoneal cancer, and fallopian tube cancer.
PURPOSE: This randomized phase II trial is comparing the side effects of three combination
chemotherapy regimens and to see how well they work in treating patients with stage IIB,
stage IIC, stage III, or stage IV ovarian epithelial cancer, primary peritoneal cancer, or
fallopian tube cancer.
Phase:
Phase 2
Details
Lead Sponsor:
Canadian Cancer Trials Group
Collaborators:
Cancer Research UK Grupo Español de Investigación en Cáncer de Ovario National Cancer Institute (NCI) Southwest Oncology Group