Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome
Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
Acute respiratory distress syndrome (ARDS) in combination with multi-organ dysfunction
syndrome (MODS) is a life-threatening condition, particularly when treatment modalities such
as extracorporeal membrane oxygenation (ECMO) and catecholamine administration have failed to
treat the severe condition. In this study, the investigators report patients who responded to
intrapleural steroid instillation (IPSI) while being unresponsive to conventional treatment
(use of intravenous steroids, nitric oxide inhalation, high-frequency oscillatory
ventilation, or ECMO) for treatment of critical illnesses such as ARDS in combination with
MODS.