Intrathecal Atropine Versus Intravenous Ondasetron in Post Operative Nausea Due to Intrathecal Morphine

• Status: Not yet recruiting
• Trial end date: 2022-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare between intrathecal atropine versus preoperative administration of IV ondansetron in decreasing incidence of post operative nausea and vomiting related to intrathecal opioids in post operative period in perineal surgery as regard : efficacy and side effects .

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sohag University
• Treatments: Atropine; Bupivacaine; Ondansetron

Criteria

Inclusion Criteria:

• Age between ( 18 - 45 ) years.

• Body mass index between ( 18.5 - 35 )

• patients undergoing perineal surgery as anal fissure , piles and rectocele

• patients receiving bupivacaine ( 20 mg / 4 ml ) as spinal anesthesia

• Patinets with physical status 1 or 2 according to ASA classification

Exclusion Criteria:

• Patient refusal .

• Any contraindication of neuraxial block as : coagulopathy , skin infection at injection site or bacteremia , hypovolemia and shock , history of allergy to L.A , sever aortic stenosis or mitral stenosis ……… etc

• Patients with physical status other than 1 and 2 according to ASA classification

• Those with history of nausea and vomiting , also those who received anti emetic drugs in last 2 hours of operation .

• Allergy to any of the drug included in this study .