Intrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CS

• Status: Completed
• Trial end date: 2019-08-28
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to evaluate the prophylactic use of low dose atropine and comparing it to metoclopramide for reducing intraoperative nausea and vomiting during cesarean section under spinal anesthesia

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Atropine; Metoclopramide

Criteria

Inclusion Criteria:

• Patients with ASA physical status class I or II; indications for CS other than fetal or maternal pathology and surgery scheduled for within 4 days of physiological term will be included in this study

Exclusion Criteria:

• Height < 150 or > 180 cm

• Body mass index (BMI) >35 kg/m2

• Active labor or emergency CS

• Emesis gravidarum

• Multifetal pregnancy

• Fetal distress

• Associated medical problem with pregnancy (as hypertension, diabetes mellitus, hepatic impairment or renal impairment)

• Obstetric problem (as placenta previa or placental abruption)

• Contraindication for central neuraxial block

• History of adverse reaction to any study medication

• History of antiemetic drug use

• Refusal to undergo regional anesthesia