Intrathecal Clonidine in Cesarean Section May Lead to Worse Blood Gas Results in the Newborns

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate effects of intravenous clonidine in acute and chronic post-cesarean pain, possible adverse effects over mother-newborn pair, in comparison to intrathecal adjuvant clonidine and placebo.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo General Hospital
• Treatments: Bupivacaine; Clonidine; Fentanyl; Morphine

Criteria

Inclusion Criteria:

• term pregnancy;

• elective cesarean (no labor).

Exclusion Criteria:

• multiple pregnancy;

• moderate or several systemic disease, categorized as American Society of Anesthesiology physical status (ASA) higher or equal to 3;

• contraindications for spinal anesthesia;

• contraindications for the drugs involved in the study;

• uncontrolled high blood pressure or diabetes mellitus in need of insulin therapy;

• intravenous psychotropic drugs users;

• previously known malformation on the fetus;

• patients with previous history of chronic pain.