Intrathecal Dexmedetomidine Versus Intrathecal Morphine Inpatients Undergoing Cardiac Valve Replacement Surgeries

• Status: Not yet recruiting
• Trial end date: 2024-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Comparison between the effects of intrathecal morphine versus intrathecal dexmedetomidine on analgesia and respiratory function, in open heart surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexmedetomidine; Morphine

Criteria

Inclusion Criteria:

• Cardiac patient scheduled for elective open heart valve replacement surgery.

Exclusion Criteria:

• • Patient refusal

• Coagulation disorders

• History of known allergy to the used drugs.

• Combined procedures (e.gif combined with coronary artery bypass or aortic root surgeries).

• If thoracotomy or min-sternotomy is planned for the surgery.

• Re-do and emergency surgeries.

• History of chronic chest diseases (COPD or IPF).

• History of thoracotomy, pneumothorax, pneumomediastinum, phrenic nerve injury (as evident by the presence of paralysis of the ipsilateral hemidiaphragm when examined preoperatively).

• Neuromuscular diseases.

• Brain injuries.