Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery
Status:
Not yet recruiting
Trial end date:
2023-10-30
Target enrollment:
Participant gender:
Summary
Anorectal problems, such as hemorrhoids, fistula, fissures, Etc., often require surgical
treatment. Patients often have postoperative pain after these surgeries, which increases
discomfort and hospital length of stay. The efficacy of oral non-opioids in the treatment of
such pain is poor. Hydromorphone is an opioid analgesic commonly used orally or intravenously
for postoperative pain management. We designed this trial to investigate the efficacy and
safety of intrathecal (delivery directly to the spinal cord during spinal anesthesia) single
dose hydromorphone versus intrathecal placebo in treating postoperative pain among human
subjects after anorectal surgery, but also the recovery of postoperative motor capacity in
these human subjects.
Phase:
Phase 2
Details
Lead Sponsor:
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine