Intrathecal Injection of Pethidine Plus Dexamethasone Versus Bupivacaine Alone

• Status: Active, not recruiting
• Trial end date: 2022-07-15
• Target enrollment: 0
• Participant gender: All

Summary

Bupivacaine is commonly used as a sole agent for spinal anesthesia unlike pethidine. Pethidine (meperidine) is a unique opioid. In addition to its analgesic activity, it also has significant local anesthetic activity. This property enables it to be used as the sole agent for spinal anesthesia

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Zagazig University
• Treatments: Bupivacaine; Dexamethasone; Meperidine

Criteria

Inclusion Criteria:

• Patient acceptance.

• Patients scheduled for lower extremity orthopedic surgery

• Both sex

• Patient's age >18 years.

• Patients with American Society of Anaesthesia (ASA)physical status I, II.

Exclusion Criteria:

• Patient's age ≤18 years.

• Uncooperative patients and patients with psychological problems.

• Patients with contraindications to spinal anesthesia.

• Patients with contraindications to bupivacaine or dexamethasone or pethidine.

• Patients with ASA physical status III and IV.

• Morbid obesity (BMI >35).