Intrathecal Morphine and Local Infiltration Analgesia in Total Knee Arthroplasty
Status:
Unknown status
Trial end date:
2020-09-01
Target enrollment:
Participant gender:
Summary
Double-blinded randomized control study investigating intrathecal morphine as an additive to
spinal anesthesia in patients undergoing elective total knee arthroplasty. The investigators
aim to include a total of 120 patients, randomized to two equal groups. Participants in the
intervention group are administered intrathecal 0,2mg morphine and 12,5mg bupivacaine for
spinal anaesthesia. Participants in the placebo group are administered 12.5mg bupivacaine and
saline to match the volume of intervention goup. Primary end points are opioid consumption
and possible adverse effects.