Intrathecal Morphine for Unilateral Total Knee Arthroplasty

• Status: Completed
• Trial end date: 2019-07-31
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates postoperative numerical pain score and systemic opioid requirement within 48 hours for unilateral total knee arthroplasty. Comparing among 3 groups of intrathecal morphine; 0,50, 100 ug with multimodal analgesia.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Bupivacaine; Morphine

Criteria

Inclusion Criteria:

• Aged more than 18 years old undergoing unilateral total knee arthroplasty

• American Society of Anesthesiologists physical status classification 1-3

Exclusion Criteria:

• Participants deny to enroll the study

• Allergy to local anesthetics, opioid and NSAIDs

• Hepatic disease

• Contraindication for neuraxial block or adductor canal block

• Uncontrolled cardiovascular disease

• Creatinine clearance less than 50 ml/min