Overview

Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures

Status:
Completed
Trial end date:
2019-10-22
Target enrollment:
Participant gender:
Summary
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study. The objective of this study is to investigate the efficacy and safety of a single intrathecal injection of Paracetamol 3% (30 mg/mL) administered at 3 doses to 3 active treatment groups, as compared to placebo, for post-operative analgesia in knee procedures up to 40 min duration performed under spinal anaesthesia with Chloroprocaine HCl 1%.
Phase:
Phase 2
Details
Lead Sponsor:
Sintetica SA
Collaborator:
Cross Research S.A.
Treatments:
Acetaminophen
Anesthetics
Chloroprocaine
Pharmaceutical Solutions
Procaine