Intratracheal Dexmedetomidine Versus Lidocaine in Eye Surgery
Status:
Recruiting
Trial end date:
2022-05-30
Target enrollment:
Participant gender:
Summary
Cough during emergence from general anesthesia is considered a critical event as it may lead
to surgical bleeding laryngospasm hemodynamic instability and could be life-threatening in
patients who are at risk of complications related to increases in intracranial or intraocular
pressure. Lidocaine administration has been widely used for reducing cough during extubation
due to its simplicity and lack of serious adverse effects; There are two major routes for
lidocaine administration systemic intravenous injection and local direct application on the
laryngeal inlets such as spraying lidocaine on the supraglottic and subglottic regions or
applying lidocaine jelly or sprayed. Dexmedetomidine is a potent alpha 2 selective
adrenoceptor agonist and the most characteristic features include sympatholytic sedation
analgesia and lack of respiratory depression. The aim of this study is to compare the effect
of intratracheal dexmedetomidine and lidocaine on cough reflex in cataract surgery.