Intraureteral Lidocaine for Post-Ureteroscopy Pain

• Status: Unknown status
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents. Placements of these stents include pain, bladder irritability, infection, migration, encrustation and stones.

Pain is one of most significant problem of ureteral stents. There are no satisfactory measures to deal with this problem. A novel approach to manage the pain is to load a drug onto ureteral stent and deliver the drug into the urinary tract at controlled release rate.

Lidocaine has been proven to be effective for management of the pain associated with interstitial cystitis. This agent has the potential for management of post-URS pain.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Queen's University
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Patient undergoing URS for treatment of a urinary calculus who requires placement of ureteral stent on a string

• Able to undergo a general anaesthetic

• At least 18 years old

• Willing and able to complete patient symptom questionnaires

Exclusion Criteria:

• Solitary Kidney

• Renal failure

• Anatomic bladder or ureteral abnormality

• Uncorrected coagulopathy

• Previous cystectomy or urinary diversion

• Neurogenic bladder

• Interstitial cystitis

• Transplanted kidney

• Pregnancy

• Requires an indwelling catheter

• Recurrent urinary tract infections

• Requires an indwelling stent

• Pelvic kidney

• Requires bilateral treatment/stents

• Previous bladder or ureteral reconstructive surgery

• Ureteral perforation during procedure

• Ureteral stenting, within one month of URS

• Known sensitivity to lidocaine

• Febrile at time of randomization or treatment

• Requires spinal anaesthetic