Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

Intrauterine injection of hCG around the time of implantation may increase endometrial Treg cells and improve implantation. It has been demonstrated that regulatory T cells expand during pregnancy. hCG was found to be secreted by the embryo immediately after fertilization and has chemoattractant properties to Treg cells.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Egyptian IVF-ET Center
• Treatments: Chorionic Gonadotropin

Criteria

Inclusion Criteria:

• Male factor infertility

• Ovulatory factor infertility

• Unexplained infertility

• Female age less than 39

Exclusion Criteria:

• Azoospermia

• Tubal factor infertility

• Pelvic endometriosis