Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty

• Status: Recruiting
• Trial end date: 2030-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to evaluate if intravenous steroid supplementation can provide advantages over routine analgesia protocols in terms of post-operative symptoms (pain and nausea), length of hospital stay, shoulder range of motion, function and patient satisfaction

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Christian Candrian
• Treatments: Dexamethasone

Criteria

Inclusion Criteria:

• Patients undergoing unilateral primary total anatomical or reverse shoulder arthroplasty (Total Shoulder Arthroplasty)

• Patients with a BMI >18.5 and <35

• Patients able to provide informed consent and follow all the study procedures as indicated by the protocol

• Informed Consent as documented by signature

Exclusion Criteria:

• Contraindications to steroids

• Revision and post-traumatic TSA

• Active steroid or immunosuppressive therapy in the last 30 days before the operation

• Pregnant or breast-feeding women

• Presence of other clinically significant concomitant disease states (ASA IV)

• Uncontrolled diabetes mellitus

• Contraindications to Non-steroidal anti-inflammatory drugs

• Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus), gout, rheumatic arthritis

• Known or suspected non-compliance, drug or alcohol abuse

• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.

• Participation in another study with investigational drug within the 30 days preceding and during the present study

• Previous enrolment into the current study

• Enrolment of the investigator, his/her family members, employees and other dependent persons