Intravenous Dexamethasone Effectiveness in Post Caesarean Section Analgesia
Status:
Completed
Trial end date:
2021-01-04
Target enrollment:
Participant gender:
Summary
The management of postpartum pain is essential to ensure early rehabilitation for
parturients. Intravenous dexamethasone has a potent analgesic action when used in the context
of general anesthesia. Nevertheless, it remains poorly studied in combination with spinal
anesthesia (SA). The aim of this study was to assess the analgesic effect of intravenous
dexamethasone after caesarean section under SA.
Methods: We conducted a prospective, randomized, double-blinded study including 84 ASA II-III
parturient at term who were proposed for caesarean section under SA. Parturient were
randomized into two groups: Dexamethasone group (DG) who received 8mg of intravenous
dexamethasone (2ml) immediately after SA and placebo group (PG) who received 2ml of isotonic
saline. The analgesic protocol was standardized and we opted for Tramadol as rescue
analgesic. The main outcome is the use of Tramadol in the first 24 hours postpartum..