Intravenous Dexamethasone to Increase the Analgesic Duration of Interscalene Block

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Interscalene brachial plexus block provides excellent but time limited analgesia. Intravenous dexamethasone increases the analgesic duration of a single-shot interscalene block with ropivacaine for shoulder arthroscopic surgery. We want to evaluate the effect of two different doses (dexamethasone 10 mg i.v. vs 4 mg i.v. vs placebo) on the analgesic duration of a single-shot inter scalene block. Our study hypothesis is that dexamethasone 4 mg i.v. is equivalent to dexamethasone10 mg i.v. in prolonging the analgesic duration of a single-shot interscalene block with ropivacaine.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maisonneuve-Rosemont Hospital
• Treatments: Analgesics; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Elective shoulder arthroscopy under ropivacaine single-shot interscalene brachial plexus block anesthesia (rotator cuff repair and shoulder decompression)

• ASA I-III

• Age 18-80 years old

Exclusion Criteria:

• Any contraindication to interscalene brachial plexus block anesthesia

• Interscalene brachial plexus block failure

• Known local anesthetics allergy

• Dexamethasone allergy or intolerance

• Any contraindication to acetaminophen

• Any contraindication to morphine or hydromorphone

• Brachial plexus neuropathies

• Chronic pain syndrome other than shoulder pain

• Routine use of opioid medication

• Routine use of systemic corticosteroid

• Pregnancy

• Weight below 50 kilograms

• Incapability to understand a numeric verbal pain scale

• Incapability to consent

• Patient refusal