Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
Status:
Completed
Trial end date:
2018-10-13
Target enrollment:
Participant gender:
Summary
In this single-centre, double-blinded, randomized controlled superiority trial, 189
participants having outpatient, arthroscopic shoulder surgery will be randomized into 3 equal
sized groups. All participants will receive a standardized interscalene brachial plexus block
and 4mg of dexamethasone or 50mcg of dexmedetomidine or both intravenously just prior to
their surgery. The purpose of this study is to provide a head to head comparison of two types
intravenous adjuncts to ISB, corticosteroids and alpha 2 agonists, and determine if their
combination, or either one alone provides superior postoperative analgesia in arthroscopic
shoulder surgery patients, as well as possibly show a synergistic relationship between the
two adjuncts. The investigators hypothesize the combination of adjuncts will provide a longer
duration of analgesia compared to either single agent.