Intravenous Dexmeditomidine for Prevention of Spinal Anesthesia Induced Shivering.
Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
Intraoperative and post operative shivering is a common problem encountered in operating
rooms and recovery suites. Shivering under spinal anesthesia has an incidence of 40-60%.
Shivering is not only uncomfortable for the patient; additionally it increases minute oxygen
consumption, subjecting the patient to a higher risk of cardiovascular complications. A
variety of drugs like pethidine, fentanyl, alfentanil, sufentanil, buprenorphine, doxapram,
clonidine, and ketanserin, are reported to be effective in suppressing postoperative
shivering, yet an ideal drug/ method to be explored. Dexmeditomidine, a sedative and
analgesic, may control shivering without significant adverse effects, like nausea and
vomitting and respiratory depression.
The study design will be randomized controlled parallel trials with sample size of 80,They
will be randomized into two equal groups. One group will receive 10 microgram Inj.
Dexmeditomedine while the other will recieve inj. normal saline as placebo. They will be
assessed for intra- and postoperative shivering.