Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes

• Status: Recruiting
• Trial end date: 2022-11-26
• Target enrollment: 0
• Participant gender: All

Summary

Pancreaticoduodenectomy (PD), more commonly known as Whipple's surgery is the mainstay treatment for pancreatic head and periampullary cancer. Factors contributing to PD outcomes are broadly categorized to disease-related, patient-related and operative factors. Whereas an inexhaustible list of study exists on looking at reducing PD complication rates with respect to the above-mentioned factors, it was only recently that more attention has been given to the impact of perioperative and intraoperative fluid regimes on PD outcomes. This study takes interest in the impact of intraoperative fluid regimes on PD outcomes. The objective of this investigation is to compare the outcomes with the use of intraoperative intravenous human albumin versus standard intraoperative fluid regimes.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universiti Kebangsaan Malaysia Medical Centre

Criteria

Inclusion Criteria:

• All patients undergoing pancreaticoduodenectomy that can consent to the study

Exclusion Criteria:

• Patients with known allergy to human albumin

• Patients of American Society of Anaesthesiologist (ASA) physical status class 3 and above.