Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions

• Status: Completed
• Trial end date: 2016-10-28
• Target enrollment: 0
• Participant gender: All

Summary

This is a clinical trial to evaluate the intravenous administration of indocyanine green (ICG) as a method of intra-thoracic lesion localization. The primary purpose is to determine if intravenous ICG allows us to identify intra-thoracic lesions.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Brigham and Women's Hospital

Criteria

Inclusion Criteria:

• Patients with intra-thoracic lesions that require resection for therapeutic or diagnostic purposes as recommended by their thoracic surgeon.

• 18 years of age or older

• Documented, signed, dated informed consent obtained prior to any study specific procedures being performed

Exclusion Criteria:

• Subjects who do not wish to have subsequent surgical resection

• A medical condition such as uncontrolled infection or cardiac disease that, in the opinion of the treating surgeon, makes resection unreasonably hazardous for the patient

• Pre-operative spirometry that suggests the patient is at high risk or cannot undergo resection of the primary tumor.

• Iodide or seafood allergy