Intravenous Iron: Measuring Response in Anemic Surgical Patients

• Status: Completed
• Trial end date: 2012-03-01
• Target enrollment: 0
• Participant gender: All

Summary

20 Patients will be recruited with confirmed colorectal adenocarcinoma and anemia who are planned to undergo surgery. All patients will be treated with a single dose of 1g intravenous ferric carboxymaltose (FERINJECT).

It is hypothesized that intravenous iron supplementation is efficacious at raising haemoglobin levels and reduced blood transfusion requirements.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nottingham University Hospitals NHS Trust
• Treatments: Ferric Compounds

Criteria

Inclusion Criteria:

• Age > 18 years

• Diagnosed with colonic or rectal adenocarcinoma

• Defined date of operation at least 14 days from recruitment to study

• Confirmed anemia

• Females of child bearing age must agree to use a medically accepted form of contraceptive

Exclusion Criteria:

• Patient's who are unable to consent

• Recognized allergy or intolerance of the study drug or excipients

• Patients with previous or current hematological disease that in the investigators' opinion would confound the diagnosis of anemia