Intravenous Iron vs. Oral Iron Supplementation for Postpartum Anemia
Status:
Recruiting
Trial end date:
2022-12-15
Target enrollment:
Participant gender:
Summary
This trial will be a comparative pragmatic open label feasibility randomized controlled trial
of oral daily versus IV iron in anemic postpartum patients.
Two randomly assigned groups will be compared during the postpartum period:
1. Oral Iron group: Ferrous sulfate 325 mg (65 mg elemental iron) by mouth for a total of 6
weeks TID.
IV placebo in sodium chloride 0.9% 500mL IV infusion will be given before discharge home
over 1 hour preceded by placebo test dose IV infusion of 100mL 0.9% sodium chloride.
2. IV Iron group: Low molecular weight iron dextran (infed) 1000mg in sodium chloride 0.9%
500mL IV infusion over 1 hour preceded by test dose 25 mg IV low molecular weight iron
dextran infusion in 100mL 0.9% sodium chloride.
2.1 Oral placebo will be given by mouth for a total of 6 weeks TID.