Overview

Intravenous Lacosamide Compared With Fosphenytoin in the Treatment of Patients With Frequent Nonconvulsive Seizures

Status:
Completed
Trial end date:
2015-07-01
Target enrollment:
Participant gender:
Summary
This a phase 2 study comparing the efficacy of intravenous (IV) lacosamide (LCM) with IV fosphenytoin (fPHT) in controlling frequent nonconvulsive seizures (NCSs), the Adverse Events profile of LCM compared with fPHT when used to treat frequent NCSs, and length of stay in an intensive care unit for subjects treated with LCM versus subjects treated with fPHT. The trial will include a preacute-treatment period, an acute-treatment period, a postacute-treatment period, and a long-term follow-up period.
Phase:
Phase 2
Details
Lead Sponsor:
Aatif Husain
Collaborator:
UCB Pharma
Treatments:
Fosphenytoin
Lacosamide
Phenytoin