Overview

Intravenous Pantoloc In Aspirin-Induced Ulcer Bleeding

Status:
Completed
Trial end date:
2006-09-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of the study is to investigate whether intravenous infusion of pantoprazole (Pantoloc) is effective in preventing recurrent bleeding in patients who present with acute ulcer bleeding and continue to use aspirin
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Chinese University of Hong Kong
Treatments:
Aspirin
Criteria
Inclusion Criteria:

- Patients received daily anti-platelet therapy for vascular prophylaxis before
admission and will continue need to do so

- Patinets with bleeding peptic ulcers;ulcer actively bleeding or with SRH (Forrest I,
IIa and IIb ulcers)

- Endoscopic haemostasis achieved

Exclusion Criteria:

- Presence of ulcer complication precluding endoscopic treatment such as gastric outlet
obstruction or ulcer perforation mandating surgical intervention.

- Concomitant use of anticoagulant, NSAIDs or steroid

- Pending to undergo cardiac interventions that need double anti-platelet agent

- Pregnancy

- Terminal illness, or cancer