Intravenous Regional Analgesia

• Status: Not yet recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Ketorolac

Criteria

Inclusion Criteria:

• American Society of Anesthesiologists physical status I or II

• Elective unilateral lower limb orthopedic surgery with tourniquet under spinal anesthesia

Exclusion Criteria:

• Pregnant females

• Body mass index ≥ 35 kg/m2

• Allergy to ketorolac

• Had renal, asthmatic, vascular (Raynaud's syndrome) disease, hematological anemias

• Had any history of gastrointestinal tract inflammation, bleeding, ulceration, or perforation besides

• Edema in the operated limb grade ≥ 3