Intravenous Remifentanil Patient-controlled Analgesia (PCA) and Epidural Patient Controlled Epidural Analgesia (PCEA) for Labor Analgesia

• Status: Completed
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

Women requesting analgesia do not always wish to receive a potent analgesic method, and may fear the risks of epidural analgesia.

Study Aim: To determine whether remifentanil is effective for labor analgesia when compared with standard treatment (epidural analgesia).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hadassah Medical Organization
• Treatments: Bupivacaine; Remifentanil

Criteria

Inclusion criteria:

• Healthy women

• American Society of Anesthesiologists physical status class I or II

• Body weight less than 110 kg

• In active labor (including induced labor and premature rupture of membranes)

• Cervical dilatation at 2-6 cm

• Regular contractions

• Age between 18 and 40 years old

• Gestational age greater than 36 completed weeks

• Singleton pregnancy and vertex presentation

Exclusion criteria:

• Contraindication for epidural analgesia (bleeding diathesis, neuropathy, severe scoliosis, previous spine surgery, local anesthetic allergy)

• Narcotic administration in the previous 2 hours

• Previous uterine surgery

• Pre-eclampsia and the inability to adequately understand the consent form

• Blocked nose, and any indication patient for whom epidural analgesia is medically indicated (cardiac disease, suspected difficult airway)