Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection
Status:
Not yet recruiting
Trial end date:
2025-06-30
Target enrollment:
Participant gender:
Summary
Intra-operative blood loss of huge meningioma resection patients on average was over 1000ml.
Intra-operative massive hemorrhage was associated with longer hospital of stay, higher
expense, and higher mortality. Previous studies indicated intra-operative tranexamic acid
infusion would decrease blood loss for cardiac, trauma and obstetric procedures. However,
limited researches focusing on the effect of tranexamic acid in neurosurgery population, with
heterogenous pathologies. The purpose of this study was to investigate the effect of
tranexamic acid on intra-operative blood loss in patients undergoing huge meningioma
resection.