Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to scientifically evaluate two different management strategies for perforated appendicitis.

The hypothesis is that early discharge with oral antibiotic therapy may result in a dramatic decrease in medical care expenses for the patient.

The primary outcome variable between the two strategies is abscess rate.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Children's Mercy Hospital Kansas City
• Treatments: Ampicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Ceftriaxone; Clavulanic Acid; Clavulanic Acids; Metronidazole

Criteria

Inclusion Criteria:

• Identifiable hole in the appendix or stool in the abdomen at the time of appendectomy

Exclusion Criteria:

• Known immune deficiency

• Abscess identified on pre-op imaging

• Another condition affecting surgical decision making or recovery (e.g. hemophilia, severe cardiac or respiratory co-morbidities).