Introducing PrEP Into HIV Combination Prevention - Kenya
Status:
Unknown status
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
Daily oral PrEP will be delivered to men who have sex with men (MSM), female sex workers
(FSWs) and young women (YW) as part of a defined package of HIV combination prevention
intervention for 12 months in 5 sites in Kenya. The project will assess adherence, adverse
events, side effects, user satisfaction, cost, facility preparedness and provider
competencies. PrEP eligibility and screening tools for MSM, YW and FSWs will be piloted and
validated. Pregnant women will be enrolled in a sub-group and followed through 12 months
post- partum to measure mother and infant outcomes that include health status, birth
outcomes, birth defects, risk behavior and PrEP adverse effects. With lessons from initial
PrEP studies in West and Central Africa, this project will apply good participatory practice
guidelines through 1) continuous engagement with communities of FSWs, YW and MSM and 2)
development and use of a communication engagement and advocacy strategy that will provide
correct information, address attitudes and concerns whilst increasing demand for PrEP uptake.
The actual cost of delivering HIV combination prevention which includes PrEP will also be
assessed and cost effectiveness modeled.
Phase:
N/A
Details
Lead Sponsor:
LVCT Health
Collaborators:
AVAC Bar Hostess Empowerment & Support Programme Bill and Melinda Gates Foundation Centres for Disease Control and Prevention, Kenya. Gay and Lesbian Coalition Kenya Health Options for Young Men with AIDS/STI Imperial College London International AIDS Vaccine Initiative ISHTAR MSM Kenya Sex Workers Alliance London School of Hygiene and Tropical Medicine National AIDS and STI Control Programme National AIDS Control Council Nyanza Western Kenya LGBTI Coalition O' Neill Institute Results for Development Sex Workers Outreach Project World Health Organization
Treatments:
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination