Intubation Conditions Achieved With Rapid Co-administration of Rocuronium and Propofol Versus Classical Induction

• Status: Not yet recruiting
• Trial end date: 2022-11-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess and compare the conditions for tracheal intubation obtained with Modified Time Principle Induction (MTPI) and that obtained with classic induction (CI). This study will compare the efficiency of tracheal intubation with the two induction techniques, as well as evaluate for potential adverse events.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston

Criteria

Inclusion Criteria:

• BMI >30 kg/M2 or Mallampati class III or IV

• Requiring general anesthesia and endotracheal intubation

Exclusion Criteria:

• Acute and chronic respiratory disorders, including Chronic obstructive pulmonary disease (COPD) and asthma

• American Society of Anesthesiologists (ASA) physical status classification ≥ III

• Emergency surgery

• Induction requiring cricoid pressure

• Patients requiring awake intubation

• Pregnant women

• Patients who require an induction dose of propofol less than 1 mg/kg

• Untreated ischemic heart disease

• Contraindication to mask ventilation

• Allergy to propofol, rocuronium, or Sugammadex