Overview
Intubation Conditions After RSI Using Rocuronium With Ephedrine Pretreatment
Status:
Not yet recruiting
Not yet recruiting
Trial end date:
2023-09-01
2023-09-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
This trial will study if ephedrine pretreatment before low doses of rocuronium (0.6 or 0.8 mg/kg) would provide similar intubating conditions as with the high dose of 1.2 mg/kg in patients undergoing RSII.Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Ain Shams UniversityTreatments:
Ephedrine
Rocuronium
Criteria
Inclusion Criteria:- ASA physical status I or II
Exclusion Criteria:
- Neuromuscular disease: myopathies
- On drugs that interact with the neuromuscular junction or ephedrine
- Cardiovascular disease: hypertension or ischemic heart disease
- Increased risk of pulmonary aspiration:
- GERD
- Pregnancy
- Anticipated airway difficulties:
- Mallampati grade III or IV
- Obesity (BMI ≥30 kg/m2),
- Hypersensitivity to any of the study drugs