Inulin and S. Salivarius Reduce Halitosis

• Status: Completed
• Trial end date: 2015-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Halitosis associated with tongue coating results from the production of volatile sulfur compounds by bacterial action. The use of prebiotics and probiotics might be useful in treating such condition. The aim of this study was to evaluate the effect of the prebiotic inulin combined with the probiotic Streptococcus salivarius (SS) on halitosis by coating.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidade de Passo Fundo
• Collaborator: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Criteria

Inclusion Criteria:

• adult patients with halitosis by tongue coating;

• participants must accept to participate in the study;

• tongue coating identified by oral examination;

• halitosis must be confirmed by the organoleptic test.

Exclusion Criteria:

• halitosis for other conditions, including periodontal diseases and non-oral conditions;

• use of antibiotics in the last 30 days;

• active smoking (>10 cigarettes/day);

• alcohol consumption (>2 drinks/day);

• report of pregnancy or breastfeeding;

• report of systemic diseases, including diabetes, kidney failure and hepatic cirrhosis.