Investigating Composite Biomarkers for Pain Catastrophizing
Status:
Not yet recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
Pain is a complex, multidimensional, and subjective experience; and although, investigators
use a single word "pain", to describe our perception, multiple mechanisms contribute to the
generation and maintenance of pain. To help diagnosing and improving pain management, there
is a need for developing tools. These tools may include measurements of substances, or
biomarkers, in the blood; e.g. small molecules called microRNA and proteins. In these
experiments, the investigators would like to investigate how the psychological response to
stress and pain alters the impulses in the brain and the content of microRNA and proteins in
the blood. The future aim is to identify patients in high risk of developing and maintaining
chronic pain and to be able to treat chronic pain efficiently.