Investigation of Analgesic and Anti-hyperalgesic Effect of Opioids in Experimental Pain

• Status: Completed
• Trial end date: 2010-01-01
• Target enrollment: 0
• Participant gender: Male

Summary

To compare the analgesic and anti-hyperalgesic effect of Buprenorphine and Fentanyl against experimental pain in skin, muscle and bone. The study will be performed with healthy volunteers.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Treatments: Analgesics; Buprenorphine; Fentanyl

Criteria

Inclusion Criteria:

• written informed consent

• men > 18 years

Exclusion Criteria:

• women

• known allergy against the investigated drugs

• ongoing participation in other experiments or participation in other experiments 14 days before screening

• previously pain or psychiatric conditions

• simultaneously use of pain killers

• alcohol

• previously drug-addict or member of family with drug-addicts

• chronic constipation

• ileus

• inflammatory bowel syndrome

• abdominal surgery within the last three months