Investigation of Bioequivalence of Ethinylestradiol (EE) and Drospirenone (DRSP) in Two Different Tablet Formulations: Yasmin and Yasmin + Levomefolate Calcium (Metafolin) & L-5-MTHF in Two Different Tablet Formulations: Levomefolate Calcium (Metafo

• Status: Completed
• Trial end date: 2007-07-01

Summary

The purpose of this study is to examine and compare the uptake of Yasmin (oral contraceptive containing drospirenone and ethinylestradiol) with or without levomefolate calcium (Metafolin, a registered vitamin supplement) in the body and to examine and compare the uptake of levomefolate calcium with or without Yasmin in the body, in healthy volunteers not using hormonal contraception.

• Phase: Phase 1

Details

• Lead Sponsor: Bayer
• Treatments: Calcium, Dietary; Drospirenone; Drospirenone and ethinyl estradiol combination; Ethinyl Estradiol; Tetrahydrofolates