Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence
Status:
Recruiting
Trial end date:
2025-05-30
Target enrollment:
Participant gender:
Summary
This is a randomized double-blind crossover trial of trospium and placebo in women with
urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and
brain MRI) at baseline, and after each course of therapy. The investigators will evaluate
functional brain changes in relation to bladder improvement in order to improve our knowledge
of the brain's role in the continence mechanism.