Investigation of Cocaine Addiction Using mGluR5 PET and fMRI
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
The proposed research program will investigate the changes in brain chemistry and circuitry
that 're-wire' the brain during chronic cocaine use, promote relapse, and complicate
treatment efforts. Currently-using and non-treatment-seeking individuals with a cocaine use
disorder will undergo a cocaine self-administration paradigm 2-5 days prior to completing
positron emission tomography (PET) and functional magnetic resonance imaging (fMRI).