Investigation of Dental Plaque and Gingival Index

• Status: Completed
• Trial end date: 2008-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Investigation of inhibitory effect of prototype toothpaste on dental plaque formation via modified gingival margin plaque index method.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Colgate Palmolive
• Treatments: Fluorides; Fluorophosphate; Listerine; Sodium Fluoride; Triclosan

Criteria

Inclusion Criteria:

• Be aged 18 to 65 years inclusive

• Have a minimum of 20 natural uncrowned teeth (excluding 3rd molars) present

• Give written informed consent

• Be in good general health

• Must discontinue oral hygiene for 24-hrs.after initial appointment.

• No known history of allergy to personal care/consumer products or their ingredients, relevant to any ingredients in the test products as determined by the dental/medical professional monitoring the study

Exclusion Criteria:

• Medical condition which requires pre-medication prior to dental visits/procedures

• Advanced periodontal disease

• 5 or more decayed, untreated dental sites

• Diseases of the soft or hard oral tissues

• Orthodontic appliances

• Abnormal salivary function

• Use of drugs that can currently affect salivary flow

• Use of antibiotics one (1) month prior to or during this study

• Use of any over the counter medications other than analgesics (i.e. aspirin, ibuprofen, acetaminophen, naproxyn)

• Pregnant or breastfeeding.

• Participation in another clinical study in the month preceding this study

• Allergic to common dentifrice ingredients.

• Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy)