Overview
Ipratropium Bromide Spray as Treatment for Sialorrhea in Children
Status:
Unknown status
Unknown status
Trial end date:
2021-01-01
2021-01-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Double-blind, clinical trial investigating the effects of ipratropium spray versus placebo spray in children with sialorrheaPhase:
Phase 2Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
London Health Sciences CentreTreatments:
BromidesIpratropium
Criteria
Inclusion Criteria:- Children and adolescents aged 5-18 with a history of excessive drooling
Exclusion Criteria:
- known hypersensitivity to ipratropium bromide
- surgery for sialorrhea within one year
- the concurrent use of acetylcholinesterase inhibitors, cholinergic agents, or
anticholinergic agents
- botulinum toxin for drooling within the preceding six months
- a history of glaucoma
- the presence of clinically significant urinary retention or outflow obstruction as
evidenced by patient history or documented urodynamic studies