Overview

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Randomized phase III trial to compare the effectiveness of irinotecan with that of combination chemotherapy in treating patients who have advanced colorectal cancer that has not responded to previous treatment. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for colorectal cancer.
Phase:
Phase 3
Details
Lead Sponsor:
National Cancer Institute (NCI)
Collaborators:
Eastern Cooperative Oncology Group
Southwest Oncology Group
Treatments:
Calcium
Calcium, Dietary
Camptothecin
Fluorouracil
Irinotecan
Leucovorin
Levoleucovorin
Oxaliplatin