Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas
Status:
Completed
Trial end date:
2015-03-01
Target enrollment:
Participant gender:
Summary
Tumours of the brain and of the central nervous system (CNS) are the most common solid
tumours in children. Amongst these, gliomas are the most frequent, although this term covers
different histological subtypes, the most frequent being astrocytoma. However, they are rare
diseases of low prevalence.
The interest in the cisplatin/irinotecan combination in brain tumours motivated a previous
pilot study at our hospital, with encouraging results. This experience, together with the
need for new strategies for high-risk pediatric gliomas has motivated the conduct of this
study.
Phase:
Phase 2
Details
Lead Sponsor:
Hospital Sant Joan de Deu
Collaborators:
Fundació Sant Joan de Déu Spanish National Health System