Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
Status:
Recruiting
Trial end date:
2024-09-01
Target enrollment:
Participant gender:
Summary
This study will examine if brain insulin resistance is a feature of major depressive disorder
(MDD) in humans using magnetic resonance imaging (MRI) measures sensitive to brain insulin
action. This study will examine adolescents, as MDD onset commonly occurs during this age,
and the impacts of cumulative medication exposure and other lifestyle-related confounds are
also lower in this age group, improving our ability to understand the underlying biology.