Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients

• Status: Unknown status
• Trial end date: 2003-12-01

Summary

The purpose of this study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be associated with a lower incidence of delirium when compared to propofol and midazolam. We hypothesize that sedation with dexmedetomidine following cardiac surgery with CPB will be associated with a lower incidence of postoperative delirium.

• Phase: Phase 4

Details

• Lead Sponsor: Stanford University
• Collaborator: Abbott
• Treatments: Dexmedetomidine; Midazolam; Propofol