Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant

• Status: Recruiting
• Trial end date: 2021-07-31
• Target enrollment: 0
• Participant gender: All

Summary

During the course of an endoscopic procedure, air has historically been used to inflate the lumen to provide adequate visualization and allow for the endoscope to advance as necessary. In many adult centers, carbon dioxide is used for insufflation for all procedures. Many pediatric centers have started using carbon dioxide for insufflation during endoscopy based on the adult studies. Few pediatric studies have been done. This study is designed to test whether carbon dioxide is associated with any negative, post-procedural, outcomes in pediatric patients.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Nebraska
• Collaborator: Children's Hospital & Medical Center

Criteria

Inclusion Criteria:

• Children 6 months to 19 years old and

• Undergoing upper endoscopy at Children's Hospital & Medical Center in Omaha, NE and

• Parents or legal guardians consent to the study

Exclusion Criteria:

• Patients and legal guardians who decline participation in the study

• Patients with chronic respiratory disease (defined as severe asthma, bronchopulmonary dysplasia and cystic fibrosis-related pulmonary disease)

• Patients with cyanotic heart disease

• Patients with an ASA status of ≥ 3.

• Patients who are wards of the state or in foster care

• Prisoners

• Patients undergoing colonoscopy only procedures or procedures not related to upper endoscopy