Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?

• Status: Completed
• Trial end date: 2019-11-21
• Target enrollment: 0
• Participant gender: All

Summary

In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative single dose intraoral submucosal corticosteroid administration and therapeutic elastic bandage application considering inflammatory symptoms' severity and health related quality of life following surgical removal of impacted third molars. The study hypothesis was formed stating that corticosteroid injection and elastic bandage application would reduce the inflammatory symptoms more than NSAID.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tokat Gaziosmanpasa University
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Dexketoprofen trometamol; Ketoprofen

Criteria

Inclusion Criteria:

• Age between 18-65 years

• American Society of Anesthesiologists (ASA) Class 1 physiological status

• Consistent radiological and clinical data

• Volunteered to participate in the study

• Surgical difficulty score above 5 which was determined according to Pederson scale.

Exclusion Criteria:

• Being out of age range

• Analgesic or antibiotic therapy history in last 30 days due to symptoms of related third molar

• Smoking cigarette

• Any pathology associated with impacted third molar

• Active complaints on preoperative examination on the day of surgery

• Immunosuppressed or diagnosed with malignancy

• Diagnosed chronic diseases such as; Diabetes mellitus (DM), hypertension, cerebrovascular event, psychiatric diseases, coagulopathies

• Autoimmune diseases

• If total operation time exceeds 45 minutes

• Patients who could not attend regular follow-up visits

• Allergy to the medications prescribed or utilized in study protocol

• Inconsistent clinical and radiological data