Is it Effective to Treat Patients With Blastocystis Hominis Infection?

• Status: Active, not recruiting
• Trial end date: 2021-09-30
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to determine whether in the setting of primary health care it is effective to treat with metronidazole returning travellers with gastrointestinal symptoms and B. hominis in the stool or not.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Lausanne Hospitals
• Treatments: Metronidazole

Criteria

Inclusion Criteria:

• ≥ 18 years

• Gastrointestinal symptoms for more than 10 days

• B. hominis in any quantity in at least one stool specimen out of 3 examined

• No other pathogenic micro-organism identified

Exclusion Criteria:

• Fever > 37.5°

• bloody diarrhoea

• weight loss > 10% of usual body weight

• significant decrease of general condition

• oncological diseases

• immune deficiencies

• known chronic intestinal diseases

• use of anti-protozoan drugs in the last 2 weeks

• use of anti-coagulant treatment or antabuse

• pregnant and lactating women