For tablets to be absorbed, the drug must dissolve after being swallowed. Drugs with low
solubility sometimes require the inert ingredients in tablets to help the drug dissolve after
being swallowed. This study uses itraconazole as an example drug with low solubility.
Itraconazole tablets with different inert ingredients and manufacturing will be administered
to healthy volunteers to see if the different inert ingredients and manufacturing impact drug
absorption.
Phase:
Phase 4
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore