Ivermectin in the Treatment of Head Lice

• Status: Completed
• Trial end date: 2004-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare 2 single doses of ivermectin as tablets with 2 single applications of malathion 0.5% lotion (Days 1 and 8) in clearing head lice, in patients who have recently used standard head lice treatments without success.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
• Treatments: Ivermectin; Malathion

Criteria

Inclusion Criteria:

• Head lice infestation confirmed by detection combing by study staff

• previous (within 6 weeks) use of a topical insecticide product

• minimum 15kg weight

• providing informed consent

Exclusion Criteria:

• pregnant or nursing patients

• households with 7 or more infested patients

• households where there are other known infested household members not participating

• head lice treatment within 2 weeks of entry

• active scalp infection

• any difficulty with combing assessment

• patient from region endemic for certain parasitic worm diseases