JS-201 Combined With Lenvatinib in the Treatment of Small-cell Lung Cancer

• Status: Recruiting
• Trial end date: 2023-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective, single-arm phase II clinical study to evaluate the efficacy and safety of JS-201 combined with lenvatinib in the treatment of small-cell lung cancer that has failed previous chemotherapy combined with PD-L1. The primary observational endpoint is ORR, and the secondary observational endpoint is PFS, OS. The intervention mode is JS201 300mg i.v Q2w, lenvatinib 8mg po. Qd.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hunan Province Tumor Hospital
• Treatments: Lenvatinib

Criteria

Inclusion Criteria:

• 1. The imaging diagnosis is the extensive stage of SCLC

• 2. The patient failed first-line EC+PD-L1 treatment

• 3 PS 0-1

Exclusion Criteria:

• 1. Diagnosed as non-small cell lung cancer

• 2. Women during pregnancy

• 3. Patients with symptomatic brain metastases

• 4. PS≥2